Mesostrato serves traditional Cretan dishes including vegan-friendly peas hummus, salads, and stuffed vine leaves in a unique setting incorporating old building ruins with real trees inside. Several reviewers appreciate the house wine and distinct local dishes such as Chaniotiko Boureki, while mentioning a casual presentation style and moderate pricing around mid-range levels. The outdoor seating and courtyard atmosphere with occasional live music create a relaxed dining experience, although some note the lack of air conditioning which can affect comfort.